DOSAGE FORM CONTAINING TRAMADOL WITH CONTROLLED 24-HOUR RELEASE AND A PROCESS FOR MANUFACTURING THE SAME

DOSAGE FORM CONTAINING TRAMADOL WITH CONTROLLED 24-HOUR RELEASE AND A PROCESS FOR MANUFACTURING THE SAME

A dosage form containing tramadol or its pharmacologically acceptable salts, wherein releasing of the active ingredient for 24 hours is controlled by a hydrophobic polymer membrane, which contains 30 to 95% by weight of the active ingredient in the form of microparticles and 5 to 25 % by weight of a...

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Bibliographische Detailangaben
Hauptverfasser: VLADOVICOVA, BEATA, KORMANOVA, VIERA, HUBINOVA, VIERA, ZELEZNIK, JURAJ
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:A dosage form containing tramadol or its pharmacologically acceptable salts, wherein releasing of the active ingredient for 24 hours is controlled by a hydrophobic polymer membrane, which contains 30 to 95% by weight of the active ingredient in the form of microparticles and 5 to 25 % by weight of a hydrophobic polymer, and a process for manufacturing the same. La présente invention concerne une forme de dosage contenant du tramadol ou ses sels pharmacologiquement acceptables qui contient 30 à 95 % en poids du principe actif sous la forme de microparticules et 5 à 25 % en poids d'un polymère hydrophobe, la libération du principe actif pendant 24 heures étant régulée par une membrane polymérique hydrophobe. L'invention concerne également un procédé de fabrication de ladite forme de dosage.