COMPOSITIONS FOR DELIVERY OF BIOLOGICALLY ACTIVE AGENTS TO SURFACES

The presently disclosed subject matter relates to compositions for delivering biologically active agent to non-biological substrates, the compositions comprising a surface-binding peptide coupled to a drug delivery vehicle, wherein the surface-binding peptide has binding affinity for the non- biolog...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	BUEHRER, BENJAMIN, MARCUS, HAMILTON, PAUL, THEODORE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BANDAGES, DRESSINGS OR ABSORBENT PADS CHEMISTRY DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS FILTERS IMPLANTABLE INTO BLOOD VESSELS FIRST-AID KITS FOMENTATION HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROSTHESES TREATMENT OR PROTECTION OF EYES OR EARS
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Beschreibung
Zusammenfassung:	The presently disclosed subject matter relates to compositions for delivering biologically active agent to non-biological substrates, the compositions comprising a surface-binding peptide coupled to a drug delivery vehicle, wherein the surface-binding peptide has binding affinity for the non- biological substrate and the drug delivery vehicle carries the biologically active agent. Also provided are methods of applying the compositions by contacting a non-biological substrate with the composition such that the composition binds non-covalently to the non-biological substrate. L'invention concerne des compositions pour fournir un agent biologiquement actif à des substrats non biologiques, les compositions comprenant un peptide de liaison à une surface couplé à un véhicule d'administration de médicament, le peptide de liaison à une surface ayant une affinité de liaison pour le substrat non biologique et le véhicule d'administration de médicament portant l'agent biologiquement actif. L'invention concerne également des procédés d'application des compositions par mise en contact d'un substrat non biologique avec la composition de telle sorte que la composition se lie de manière non covalente au substrat non biologique.