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The present invention relates to novel indoline derivatives which bind to the 5-HT2B receptor and are capable of interfering with the effects of 5-hydroxytryptamine (5-HT) at the 5-HT2B receptor; to processes for their preparation; to pharmaceutical compositions containing them; and to the use of su...

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Bibliographische Detailangaben
Hauptverfasser:	HIRST, DAVID, WOODHOUSE, KATIE, SIAN, COOPER, IAN, WARD, JOHN, GERARD, STEMP, GEOFFREY, BRUTON, GORDON, ORLEK, BARRY, SIDNEY
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to novel indoline derivatives which bind to the 5-HT2B receptor and are capable of interfering with the effects of 5-hydroxytryptamine (5-HT) at the 5-HT2B receptor; to processes for their preparation; to pharmaceutical compositions containing them; and to the use of such compounds in therapy. La présente invention concerne de nouveaux dérivés indole qui se lient au récepteur 5-HT2B et qui sont capables d'interférer avec les effets de la 5-hydroxytryptamine (5-HT) au niveau du récepteur 5-HT2B, des processus de préparation de ces dérivés, des compositions pharmaceutiques contenant ces dérivés et l'utilisation de ces composés en thérapie.