ORAL CANCER MARKERS AND THEIR DETECTION

Methods of detecting progression from precancer to cancer are provided utilizing toluidine blue staining as well as detecting allelic variation at microsatellite loci. An allelic variation in one or more locus is indicative of a progression from precancer to cancer. L'invention concerne des mét...

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Hauptverfasser:	SIDRANSKY, DAVID, CHIAFARI, FRANCIS, A, BRIDE, MARK, MAGUIRE, YU PING, ALLEN, ANTONETTE, C.P, BURKETT, DOUGLAS, D
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
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Zusammenfassung:	Methods of detecting progression from precancer to cancer are provided utilizing toluidine blue staining as well as detecting allelic variation at microsatellite loci. An allelic variation in one or more locus is indicative of a progression from precancer to cancer. L'invention concerne des méthodes permettant de détecter l'évolution d'un précancer en cancer. Ces méthodes mettent en oevre la coloration au bleu de toluidine ainsi que la détection de variations alléliques dans des loci microsatellites. Une variation allélique dans au moins un locus indique l'évolution d'un précancer en cancer.