PYRROLE-2-CARBOXAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION

PYRROLE-2-CARBOXAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION

Pyrrole-2-carboxamide derivatives, their polymorphs, stereoisomers, prodrugs, solvates, pharmaceutically acceptable salts and formulations thereof, beneficial for prophylaxis, management, treatment, control of progression, or adjunct treatment of diseases and/or medical conditions where the activati...

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Hauptverfasser: MAVINAHALLI, N., JAGADEESH, BHUNIYA, DEBNATH, KAPKOTI, S., GOBIND, WARRIER, S., JAYAKUMAR, PALLE, P., VENKATA, KUKREJKA, GAGAN, MOOKHTIAR, A., KASIM
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Pyrrole-2-carboxamide derivatives, their polymorphs, stereoisomers, prodrugs, solvates, pharmaceutically acceptable salts and formulations thereof, beneficial for prophylaxis, management, treatment, control of progression, or adjunct treatment of diseases and/or medical conditions where the activation of glucokinase would be beneficial, are disclosed. The disclosure also provides process of preparation of these pyrrole-2-carboxamides. La présente invention concerne des dérivés de pyrrole-2-carboxamide, leurs polymorphes, stéréoisomères, promédicaments, solvates, sels et formulations pharmaceutiquement acceptables, qui se révèlent utiles pour la prophylaxie, la gestion, le traitement, le suivi de la progression, ou le traitement d'appoint de maladies et/ou de pathologies où l'activation de la glucokinase devrait s'avérer bénéfique. L'invention concerne également un procédé de préparation de ces pyrrole-2-carboxamides.