COMBINATION OF CHK AND PARP INHIBITORS FOR THE TREATMENT OF CANCERS

COMBINATION OF CHK AND PARP INHIBITORS FOR THE TREATMENT OF CANCERS

A combination, comprising a checkpoint kinase (CHK) inhibitor, or a pharmaceutically acceptable salt thereof, and a poly (ADP-ribose)polymerase (PARP) inhibitor, or a pharmaceutically acceptable salt thereof is described. La présente invention concerne une combinaison comprenant un inhibiteur de la...

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Hauptverfasser: ZABLUDOFF, SONYA, SMITH, GRAEME, CAMERON, MURRAY, O'CONNOR, MARK, JAMES
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:A combination, comprising a checkpoint kinase (CHK) inhibitor, or a pharmaceutically acceptable salt thereof, and a poly (ADP-ribose)polymerase (PARP) inhibitor, or a pharmaceutically acceptable salt thereof is described. La présente invention concerne une combinaison comprenant un inhibiteur de la kinase checkpoint (CHK) ou d'un sel pharmaceutiquement acceptable de celle-ci et un inhibiteur de la poly(ADP-ribose)polymérase (PARP) ou d'un sel pharmaceutiquement acceptable de celle-ci.