SOURCE TAGGING AND NORMALIZATION OF DNA FOR PARALLEL DNA SEQUENCING, AND DIRECT MEASUREMENT OF MUTATION RATES USING THE SAME

This invention allows efficient tagging and normalization of DNA molecules prior to pooling and characterization using parallel DNA sequencing (e.g., commercially available 454 sequencers). The invention provides novel ways to process independent DNA samples (sources) so that similar numbers of mole...

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Bibliographische Detailangaben
Hauptverfasser: GLENN, TRAVIS, C, SZALAI, GABOR, J, LANCE, STACEY, L, FELDER, MICHAEL, R, JONES, KENNETH, L
Format: Patent
Sprache:eng ; fre
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