METHOD OF MANUFACTURING 1-(2-DEOXY-ALPHA-D-ERYTHRO-PENTOFURANOSYL)-5-AZACYTOSINE
This invention relates to a method of manufacturing 1-(2-deoxy-alpha-D-erythro-pentofuranosyl)-5-azacytosine by the treatment of protected alkyl or aralkyl 2-deoxy-D-erythro-pentofuranoside with silylated 5-azacytosine in the presence of Lewis acid and subsequent removal the protecting groups. L...
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| Format: | Patent |
| Sprache: | eng ; fre |
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| Zusammenfassung: | This invention relates to a method of manufacturing 1-(2-deoxy-alpha-D-erythro-pentofuranosyl)-5-azacytosine by the treatment of protected alkyl or aralkyl 2-deoxy-D-erythro-pentofuranoside with silylated 5-azacytosine in the presence of Lewis acid and subsequent removal the protecting groups.
L'invention concerne un procédé de fabrication de 1-(2-deoxy-alpha-D-erythro-pentofuranosyl)-5-azacytosine lorsque l'on traite 2-deoxy-D-erythro-pentofuranoside alkyle ou aralkyle protégé avec 5-azacytosine syliée en présence d'acide de Lewis et que l'on élimine ensuite les groupes de protection. |
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