NOVEL CARBOHYDRATE PROFILE COMPOSITIONS FROM HUMAN CELLS AND METHODS FOR ANALYSIS AND MODIFICATION THEREOF

The invention describes reagents and methods for specific binders to glycan structures of stem cells. Furthermore the invention is directed to screening of additional binding reagents against specific glycan epitopes on the surfaces of the stem cells. The preferred binders of the glycans structures...

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Hauptverfasser: MIKKOLA, MILLA, HIRVONEN, TIA, SAARINEN, JUHANI, AITIO, OLLI, LAINE, JARMO, PARTANEN, JUKKA, NATUNEN, JARI, TIITTANEN, MINNA, VALMU, LEENA, HEISKANEN, ANNAMARI, SALO, HANNA, TIITINEN, SARI, IMPOLA, ULLA, BLOMQVIST, MARIA, OLONEN, ANNE, NATUNEN, SUVI, SATOMAA, TERO, JAATINEN, TAINA, PITKAENEN, VIRVE, ANDERSON, HEIDI
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The invention describes reagents and methods for specific binders to glycan structures of stem cells. Furthermore the invention is directed to screening of additional binding reagents against specific glycan epitopes on the surfaces of the stem cells. The preferred binders of the glycans structures includes proteins such as enzymes, lectins and antibodies. L'invention concerne des réactifs ainsi que des méthodes de criblage de liants spécifiques de structures de glycanes de cellules souches. En outre, l'invention concerne le criblage de réactifs de liaison supplémentaires dirigés contre des épitopes de glycanes sur les surfaces des cellules souches. Les liants préférés des structures de glycanes comprennent des protéines telles que les enzymes, les lectines et les anticorps.