METHODS FOR INHIBITING ANGIOGENESIS AND TUMOR GROWTH BY INHIBITION OF BETA OR DELTA PROTEIN KINASE C

Treatment methods for inhibiting tumor growth and angiogenesis are described. The methods involve treatment with an inhibitor of delta protein kinase C (dPKC) or an inhibitor of beta-ll protein kinase C (ßIIPKC), in an amount effective to decrease the rate of growth of a solid tumor and/or to inhibi...

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Hauptverfasser:	KIM, SYLVIA, JEEWON, MOCHLY-ROSEN, DARIA, D
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	Treatment methods for inhibiting tumor growth and angiogenesis are described. The methods involve treatment with an inhibitor of delta protein kinase C (dPKC) or an inhibitor of beta-ll protein kinase C (ßIIPKC), in an amount effective to decrease the rate of growth of a solid tumor and/or to inhibit tumor angiogenesis. L'invention concerne des méthodes de traitement destinées à inhiber la croissance et l'angiogenèse tumorales. Ces méthodes comprennent un traitement à base d'un inhibiteur de la protéine kinase C delta (dPKC) ou d'un inhibiteur de la protéine kinase C bêta-ll (ßIIPKC), dans une quantité efficace pour réduire la vitesse de croissance d'une tumeur solide et/ou inhiber l'angiogenèse tumorale.