PENEM PRODRUGS

The invention relates to prodrugs of sulopenem of formula (I): wherein R1 is -(C2-C8)alkyl, or a solvate or hydrate thereof. The invention also relates to the preparation, formulation, and use of the prodrugs of sulopenem to treat a disorder such as an infection in a patient in need thereof. L'...

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Bibliographische Detailangaben
Hauptverfasser:	BRIGHTY, KATHERINE, ELIZABETH, MARFAT, ANTHONY, O'DONNELL, JOHN, PAUL, ANDERSON, STEPHEN, RICHARD, MCLEOD, DALE, GORDON
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to prodrugs of sulopenem of formula (I): wherein R1 is -(C2-C8)alkyl, or a solvate or hydrate thereof. The invention also relates to the preparation, formulation, and use of the prodrugs of sulopenem to treat a disorder such as an infection in a patient in need thereof. L'invention porte sur des promédicaments de sulopénème de la formule (I) : dans laquelle R1 est alkyle en (C2-C8), ou un solvate ou un hydrate de celui-ci. L'invention porte également sur la préparation, la formulation et l'utilisation des promédicaments de sulopénème pour traiter un trouble tel qu'une infection chez un patient qui a besoin d'un traitement.