NOVEL SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS

Substituted heteroaryl nitrile derivatives of Formula I, processes for their preparation, pharmaceutical compositions comprising such compounds and use of the compounds as cysteine protease inhibitors are provided. L'invention concerne des dérivés d'hétéroaryl-nitrile substitués de formule...

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Hauptverfasser: COTERON LOPEZ, JOSE-MIGUEL, FIANDOR ROMAN, JOSE, MARIA, KUSALAKUMARI SUKUMAR, SENTHIL, KUMAR
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Substituted heteroaryl nitrile derivatives of Formula I, processes for their preparation, pharmaceutical compositions comprising such compounds and use of the compounds as cysteine protease inhibitors are provided. L'invention concerne des dérivés d'hétéroaryl-nitrile substitués de formule I, leurs procédés de préparation, des compositions pharmaceutiques comprenant de tels composés et l'utilisation des composés comme inhibiteurs de cystéine protéase.