ORAL PHARMACEUTICAL FORMULATION COMPRISING A SULFONYL BICYCLIC MODULATOR OF PPAR FOR THE TREATMENT OF DISEASE

ORAL PHARMACEUTICAL FORMULATION COMPRISING A SULFONYL BICYCLIC MODULATOR OF PPAR FOR THE TREATMENT OF DISEASE

Provided herein are oral pharmaceutical formulations of 4-[cis-2,6-dimethyl-4- (4-trifluoromethoxy-phenyl)-piperazine- 1 -sulfonyl]-indan-2-carboxylic acid which may be useful as inhibitors of peroxisome proliferator activated receptors (PPARs) for the treatment or prevention of diseases such as dia...

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Bibliographische Detailangaben
Hauptverfasser: SCRANTON, SHAWN, A, GALLAGHER, JAMES, L, ROURICK, ROBYN, A
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:Provided herein are oral pharmaceutical formulations of 4-[cis-2,6-dimethyl-4- (4-trifluoromethoxy-phenyl)-piperazine- 1 -sulfonyl]-indan-2-carboxylic acid which may be useful as inhibitors of peroxisome proliferator activated receptors (PPARs) for the treatment or prevention of diseases such as diabetes, hyperglycemia, metabolic syndrome, obesity, or atherosclerosis. La présente invention concerne des formulations pharmaceutiques orales d'acide 4-[cis-2,6-diméthyl-4-(4-trifluorométhoxy-phényl)-pipérazine-1-sulfonyl]-indan-2-carboxylique qui peuvent être utilisées en tant qu'inhibiteurs des récepteurs activés par le proliférateur des peroxysomes (Peroxisome Proliferator Activated Receptors : PPAR) pour le traitement ou la prévention de maladies telles que le diabète, l'hyperglycémie, le syndrome métabolique, l'obésité ou l'athérosclérose.