NANOFIBER STRUCTURES ON ASPERITIES FOR SEQUESTERING, CARRYING AND TRANSFERRING SUBSTANCES

A device which comprises a substrate which includes a plurality of asperities, such as microneedles, extending from the surface of the substrate, and an electrospun material in contact with the substrate. The electrospun material may comprise a plurality of nanofibers which carry at least one biolog...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	SIMON, SANFORD, R, HAN, TAO, MARIN, ALEXANDER, ANDRIANOV, ALEXANDER, K, CARROLL, PETER, G, GOLUBOVIC-LIAKOPOULOS, NEVENKA, SMITH, DANIEL, J, MEYERS, DAVID, BARRETT, RENEKER, DARRELL, H
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	A device which comprises a substrate which includes a plurality of asperities, such as microneedles, extending from the surface of the substrate, and an electrospun material in contact with the substrate. The electrospun material may comprise a plurality of nanofibers which carry at least one biologically active agent. Such devices are useful as transdermal delivery devices for delivering pharmaceuticals and other biologically active agents. La présente invention concerne un substrat qui comprend une pluralité d'aspérités, telles des microaiguilles, se prolongeant depuis la surface du substrat et un matériau électrofilé en contact avec le substrat. Le matériau électrofilé peut se composer d'une pluralité de nanofibres portant au moins un agent biologiquement actif. De tels dispositifs se révèlent utiles en tant que dispositifs d'administration transdermique en vue de d'administrer des produits pharmaceutiques et d'autres agents biologiquement actifs.