TARGETED POLYLYSINE DENDRIMER THERAPEUTIC AGENT

The present invention relates generally to branched macromolecules bearing functional moieties. In particular, the invention relates to dendrimers, derived from lysine or lysine analogues, bearing a plurality of functional moieties. The invention further relates to the use of such macromolecules, pa...

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Bibliographische Detailangaben
Hauptverfasser:	KELLY, BRIAN, DEVLIN, RAZZINO, PASQUALE, HENDERSON, SCOTT, ANDREW, WILLIAMS, CHARLOTTE, CLAIRE, KRIPPNER, GUY, YEOMAN, WU, ZEMIN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	The present invention relates generally to branched macromolecules bearing functional moieties. In particular, the invention relates to dendrimers, derived from lysine or lysine analogues, bearing a plurality of functional moieties. The invention further relates to the use of such macromolecules, particularly in therapeutic applications, and compositions comprising them. La présente invention concerne d'une manière générale des macromolécules arborescentes portant des groupements fonctionnels. L'invention concerne en particulier des dendrimères, dérivés de la lysine ou d'analogues de la lysine, porteurs d'une pluralité de groupements fonctionnels. L'invention concerne en outre l'utilisation de telles macromolécules, en particulier pour des applications thérapeutiques, et des compositions les contenant.