SELF-ASSEMBLING PROTEIN HYDROGEL WITH BIO-ACTIVE PROTEIN

Protein hydrogel monomers incorporating bio-active proteins and methods for producing the same are provided. In some embodiments, the disclosed subject matter includes a protein hydrogel monomer including a bio-active protein and two alpha helices that are adapted to interact with alpha helices on o...

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Bibliographische Detailangaben
Hauptverfasser: BANTA, SCOTT, BARTON, SCOTT, CALABRESE, WHEELDON, IAN, R
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Protein hydrogel monomers incorporating bio-active proteins and methods for producing the same are provided. In some embodiments, the disclosed subject matter includes a protein hydrogel monomer including a bio-active protein and two alpha helices that are adapted to interact with alpha helices on other monomers to form coiled-coil junctions. Monomères d'hydrogel de protéines à protéines bio-actives et procédés d'élaboration correspondants. Selon certaines variantes, on décrit un monomère d'hydrogel de protéines comprenant une protéine bio-active et deux hélices alpha conçues pour interagir avec des hélices alpha sur d'autres monomères pour former des jonctions de serpentin enroulées.