COMPOSITIONS AND METHODS FOR INHIBITION OF RETROVIRAL INFECTION

Disclosed are a method for identifying a compound for inhibiting retrovirus infectivity by selectively inhibiting or disrupting the interaction between a retroviral Gag protein and a Ubc9 protein, a therapeutic compound that selectively inhibits or disrupts the interaction between a retroviral Gag p...

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Bibliographische Detailangaben
1. Verfasser:	WELDON, ROBERT, A
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Disclosed are a method for identifying a compound for inhibiting retrovirus infectivity by selectively inhibiting or disrupting the interaction between a retroviral Gag protein and a Ubc9 protein, a therapeutic compound that selectively inhibits or disrupts the interaction between a retroviral Gag protein and a Ubc9 protein, a method to inhibit retroviral infectivity in a patient, a retroviral vaccine, and methods of use thereof. La présente invention concerne un procédé d'identification d'un composé pour inhiber le pouvoir infectant d'un rétrovirus en inhibant de manière sélective ou bien en perturbant l'interaction entre une protéine gag rétrovirale et une protéine Ubc9, composé thérapeutique qui inhibe de manière sélective ou qui perturbe l'interaction entre la protéine gag rétrovirale et la protéine Ubc9. L'invention concerne un procédé d'inhibition du pouvoir infectant d'un rétrovirus chez un patient, le vaccin rétroviral ainsi que l'utilisation du dit procédé.