ORGANIC COMPOUNDS THAT INHIBIT THE CATALYTIC ACTIVITY OF THE CYCLIN-DEPENDENT CYCLIN A/KINASE 2 COMPLEX BY MEANS OF BONDING THEREOF TO A NEW PHARMACOPHORIC SITE IN THE CYCLIN MOLECULE

Isolated and/or purified peptide-type organic molecule that inhibits the enzyme activity of the cdk2/cyclin A complex, which comprises a peptide of general formula 1 and/or derivatives thereof, stereoisomers, mixtures thereof and/or the pharmaceutically acceptable salts thereof. This invention also...

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Hauptverfasser: ORZAEZ CALATAYUD, MARIA DEL MAR, BACHS I VALLDENEU, ORIOL, PEREZ PAYA, ENRIQUE, PINEDA LUCENA, ANTONIO, CANELA CANELA, NURIA
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creator ORZAEZ CALATAYUD, MARIA DEL MAR
BACHS I VALLDENEU, ORIOL
PEREZ PAYA, ENRIQUE
PINEDA LUCENA, ANTONIO
CANELA CANELA, NURIA
description Isolated and/or purified peptide-type organic molecule that inhibits the enzyme activity of the cdk2/cyclin A complex, which comprises a peptide of general formula 1 and/or derivatives thereof, stereoisomers, mixtures thereof and/or the pharmaceutically acceptable salts thereof. This invention also protects a composition containing it and use thereof in the preparation of a medicinal product for the treatment of cancerous processes. Molécula orgánica de carácter peptídico, aislada y/o purificada, inhibidora de Ia actividad enzimática del complejo cdk2 - ciclina A, que comprende un péptido de fórmula general 1 y/o sus derivados, estereoisómeros, mezclas de los mismos, y/o sus sales farmacéuticamente aceptables. Esta invención también protege una composición que Io contiene y su uso en Ia elaboración de un medicamento para el tratamiento de procesos cancerígenos. L'invention concerne une molécule organique de nature peptidique, isolée et/ou purifiée, inhibant l'activité enzymatique du complexe cdk2-cyclineA, qui comprend un peptide de formule générale 1 et/ou ses dérivés, stéréo-isomères, leurs mélanges et/ou sels pharmaceutiquement acceptables. Cette invention protège aussi une composition qui la contient et son utilisation dans la préparation d'un médicament pour le traitement de processus cancérigènes.
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This invention also protects a composition containing it and use thereof in the preparation of a medicinal product for the treatment of cancerous processes. Molécula orgánica de carácter peptídico, aislada y/o purificada, inhibidora de Ia actividad enzimática del complejo cdk2 - ciclina A, que comprende un péptido de fórmula general 1 y/o sus derivados, estereoisómeros, mezclas de los mismos, y/o sus sales farmacéuticamente aceptables. Esta invención también protege una composición que Io contiene y su uso en Ia elaboración de un medicamento para el tratamiento de procesos cancerígenos. L'invention concerne une molécule organique de nature peptidique, isolée et/ou purifiée, inhibant l'activité enzymatique du complexe cdk2-cyclineA, qui comprend un peptide de formule générale 1 et/ou ses dérivés, stéréo-isomères, leurs mélanges et/ou sels pharmaceutiquement acceptables. 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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title ORGANIC COMPOUNDS THAT INHIBIT THE CATALYTIC ACTIVITY OF THE CYCLIN-DEPENDENT CYCLIN A/KINASE 2 COMPLEX BY MEANS OF BONDING THEREOF TO A NEW PHARMACOPHORIC SITE IN THE CYCLIN MOLECULE
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