ORGANIC COMPOUNDS THAT INHIBIT THE CATALYTIC ACTIVITY OF THE CYCLIN-DEPENDENT CYCLIN A/KINASE 2 COMPLEX BY MEANS OF BONDING THEREOF TO A NEW PHARMACOPHORIC SITE IN THE CYCLIN MOLECULE

Isolated and/or purified peptide-type organic molecule that inhibits the enzyme activity of the cdk2/cyclin A complex, which comprises a peptide of general formula 1 and/or derivatives thereof, stereoisomers, mixtures thereof and/or the pharmaceutically acceptable salts thereof. This invention also...

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Bibliographische Detailangaben
Hauptverfasser:	ORZAEZ CALATAYUD, MARIA DEL MAR, BACHS I VALLDENEU, ORIOL, PEREZ PAYA, ENRIQUE, PINEDA LUCENA, ANTONIO, CANELA CANELA, NURIA
Format:	Patent
Sprache:	eng ; fre ; spa
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Isolated and/or purified peptide-type organic molecule that inhibits the enzyme activity of the cdk2/cyclin A complex, which comprises a peptide of general formula 1 and/or derivatives thereof, stereoisomers, mixtures thereof and/or the pharmaceutically acceptable salts thereof. This invention also protects a composition containing it and use thereof in the preparation of a medicinal product for the treatment of cancerous processes. Molécula orgánica de carácter peptídico, aislada y/o purificada, inhibidora de Ia actividad enzimática del complejo cdk2 - ciclina A, que comprende un péptido de fórmula general 1 y/o sus derivados, estereoisómeros, mezclas de los mismos, y/o sus sales farmacéuticamente aceptables. Esta invención también protege una composición que Io contiene y su uso en Ia elaboración de un medicamento para el tratamiento de procesos cancerígenos. L'invention concerne une molécule organique de nature peptidique, isolée et/ou purifiée, inhibant l'activité enzymatique du complexe cdk2-cyclineA, qui comprend un peptide de formule générale 1 et/ou ses dérivés, stéréo-isomères, leurs mélanges et/ou sels pharmaceutiquement acceptables. Cette invention protège aussi une composition qui la contient et son utilisation dans la préparation d'un médicament pour le traitement de processus cancérigènes.