METHODS FOR THE TREATMENT OF RENAL DISEASE, RENAL FIBROSIS AND OTHER RENAL INJURIES USING ANTI-PDGF-DD ANTIBODIES

The invention described herein relates to antibodies directed to platelet derived growth factor-DD (PDGF-DD) and uses of such antibodies. The antibodies of the invention find use as diagnostics, in the treatment of renal fibrosis, and in the treatment of renal disease, renal dysfunction and/or renal...

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Bibliographische Detailangaben
Hauptverfasser:	LAROCHELLE, WILLIAM, J, BOOR, PETER, VAN ROEYEN, CLAUDIA, R., C, VILLA, LUIGI, FLOEGE, JURGEN, KONIECZNY, ANDRZEJ, SMITHSON, GLENNDA, KUNTER, UTA, OSTENDORF, TAMMO
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The invention described herein relates to antibodies directed to platelet derived growth factor-DD (PDGF-DD) and uses of such antibodies. The antibodies of the invention find use as diagnostics, in the treatment of renal fibrosis, and in the treatment of renal disease, renal dysfunction and/or renal injury. La présente invention concerne des anticorps dirigés contre le facteur de croissance-DD dérivé des plaquettes (PDGF-DD) et les utilisations de tels anticorps. Les anticorps selon l'invention se révèlent utiles en tant qu'agents de diagnostic, pour le traitement d'une fibrose rénale, et pour le traitement d'une maladie rénale, d'un dysfonctionnement rénal et/ou d'une lésion rénale.