BENZOTRIAZEPINONE DERIVATIVES

The present invention is concerned with benzotriazepinone derivatives, their intermediates, uses thereof and processes for their production. In particular, the present invention relates to parathyroid hormone (PTH) and parathyroid hormone related protein (PTHrp) receptor ligands, (PTH-1 or PTH/PTHrp...

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Hauptverfasser: BUCK, ILDIKO, MARIA, TISSELLI, PATRIZIA, HULL, ROBERT, ANTHONY, DAVID, GRIFFIN, ERIC, SHAXTED, MARK, MCDONALD, IAIN, MAIR, SPENCER, JOHN, HARPER, ELAINE, ANNE, SYKES, DAVID, LINNEY, IAN, DUNCAN, DUNSTONE, DAVID, JOHN, AUSTIN, CAROL
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention is concerned with benzotriazepinone derivatives, their intermediates, uses thereof and processes for their production. In particular, the present invention relates to parathyroid hormone (PTH) and parathyroid hormone related protein (PTHrp) receptor ligands, (PTH-1 or PTH/PTHrp receptor ligands). The invention also relates to methods of preparing such ligands and to compounds which are useful as intermediates in such methods. La présente invention concerne des dérivés de la benzotriazépinone, leurs intermédiaires, leurs utilisations et leurs procédés de production. En particulier, la présente invention se rapporte à la parathormone (PTH) et aux ligands de récepteurs protéiques apparentés à la parathormone (PTHrp), (ligands de récepteurs PTH-1 ou PTH/PTHrp). L'invention porte, de surcroît, sur des procédés de préparation de tels ligands et des composés utiles comme intermédiaires dans de tels procédés.