PYRAZOLES FOR THE TREATMENT OF OBESITY AND OTHER CNS DISORDERS

This invention relates to compounds having pharmacological activity, to compositions containing these compounds, and to a method of treatment employing the compounds and compositions. More particularly, this invention concerns certain pyrazole derivatives, their salts and solvates. These compounds h...

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Bibliographische Detailangaben
Hauptverfasser:	DASTRUP, DAVID, PORTER HUCK, EMILIE, BENNANI, YOUSEFF, L, CAMPBELL, MICHAEL, G
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF TRAPPING
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Beschreibung
Zusammenfassung:	This invention relates to compounds having pharmacological activity, to compositions containing these compounds, and to a method of treatment employing the compounds and compositions. More particularly, this invention concerns certain pyrazole derivatives, their salts and solvates. These compounds have H3 histamine receptor binding activity. This invention also relates to pharmaceutical compositions containing these compounds and to a method of treating disorders in which histamine H3 receptor modulation is beneficial. La présente invention concerne des composés ayant une activité pharmacologique, des compositions contenant ces composés, et un procédé de traitement employant les composés et les compositions. Plus particulièrement, l'invention concerne certains dérivés de pyrazole, leurs sels et leurs solvates. Ces composés possèdent une activité de liaison au récepteur de l'histamine H3. L'invention concerne également des compositions pharmaceutiques contenant ces composés ainsi qu'un procédé de traitement de troubles dans lesquels la modulation du récepteur de l'histamine H3 est bénéfique.