BENZOXAZINONE AND BENZOXAZEPINONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS

The present invention provides a compound of formula (I) wherein X is a structure of the following formula (i), (ii), (iii), or iv G is O, or S; U is -(CR3R4)n-; W is CH2NHC(=G)R1, CH2NH-het, CH2-G-het, CH2het, C(=O)NHR2; and Y1, Y2 and Y3 are independently CH, or CF. The compounds of the present in...

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Hauptverfasser: RENSLO, ADAM, ROBERT, LUEHR, GARY, WAYNE, GAO, HONGWU, VENKATA NAGENDRA JOSYULA, VARA, PRASAD, GORDEEV, MIKHAIL
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creator RENSLO, ADAM, ROBERT
LUEHR, GARY, WAYNE
GAO, HONGWU
VENKATA NAGENDRA JOSYULA, VARA, PRASAD
GORDEEV, MIKHAIL
description The present invention provides a compound of formula (I) wherein X is a structure of the following formula (i), (ii), (iii), or iv G is O, or S; U is -(CR3R4)n-; W is CH2NHC(=G)R1, CH2NH-het, CH2-G-het, CH2het, C(=O)NHR2; and Y1, Y2 and Y3 are independently CH, or CF. The compounds of the present invention are useful as antibacterial agents. La présente invention concerne un composé de formule I où X représente une structure de formule i, ii, iii ou iv suivante; G représente O ou S; U représente -(CR3R4)n-; W représente CH2NHC(=G)R1, CH2NH-het, CH2-G-het, CH2het, C(=O)NHR2; et Y1, Y2 et Y3 représentent chacun indépendamment CH ou CF. Les composés selon la présente invention peuvent être employés en tant qu'agents antibactériens.
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The compounds of the present invention are useful as antibacterial agents. La présente invention concerne un composé de formule I où X représente une structure de formule i, ii, iii ou iv suivante; G représente O ou S; U représente -(CR3R4)n-; W représente CH2NHC(=G)R1, CH2NH-het, CH2-G-het, CH2het, C(=O)NHR2; et Y1, Y2 et Y3 représentent chacun indépendamment CH ou CF. 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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title BENZOXAZINONE AND BENZOXAZEPINONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS
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