NEUTRALIZATION OF BACTERIAL SPORES

The present invention relates to the field of bacteriology. In particular, the present invention provides compositions (e.g., a lantibiotic-based spore decontaminant (e.g., comprising nisin)) and methods of neutralizing (e.g., killing or inhibiting growth or inhibiting germination of) bacteria (e.g....

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Bibliographische Detailangaben
Hauptverfasser:	KOKAI-KUN, JOHN, F, DE LA HARPE, JON, MOND, JAMES, J
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ADHESIVES BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DYES ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MISCELLANEOUS APPLICATIONS OF MATERIALS MISCELLANEOUS COMPOSITIONS MUTATION OR GENETIC ENGINEERING NATURAL RESINS ORGANIC CHEMISTRY PAINTS PEPTIDES POLISHES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to the field of bacteriology. In particular, the present invention provides compositions (e.g., a lantibiotic-based spore decontaminant (e.g., comprising nisin)) and methods of neutralizing (e.g., killing or inhibiting growth or inhibiting germination of) bacteria (e.g., cells and spores). For example, the present invention provides nisin-based compounds (e.g., for bacterial spore decontamination) and methods of using the same in research, therapeutic and drug screening applications. L'invention se rapporte au domaine de la bactériologie. L'invention concerne en particulier des compositions (par exemple, un décontaminant pour spores à base de lantibiotique (par exemple, comprenant de la nisine) et des méthodes de neutralisation (par exemple, visant à éliminer ou à inhiber la croissance ou à inhiber la germination) de bactéries (par exemple, cellules et spores). L'invention propose par exemple des composés à base de nisine (par exemple, pour la décontamination de spores bactériennes) et des méthodes d'utilisation de ceux-ci dans la recherche, à des fins thérapeutiques et dans des applications de criblage de médicaments.