TRIOXANE DIMERS HAVING HIGH ANTICANCER AND LONG-LASTING ANTIMALARIAL ACTIVITIES

The invention provides novel trioxane dimers having formulae III, IV or V: methods for their preparation, pharmaceutical compositions containing these compounds, and methods for treating cancer and/or malaria using these compounds and compositions. L'invention concerne de nouveaux dimères de tr...

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Hauptverfasser:	BAEGE, ASTRID, C, CHANG, WONSUK, USERA, AIMEE, R, ROSENTHAL, ANDREW, SCOTT, PAIK, IKHYEON, D'ANGELO, JOHN, GAETANO, HESS, LINDSEY, CATHERINE, BORSTNIK, KRISTINA, MAIO, WILLIAM, ANTHONY, WOODARD, LAUREN, ELAINE, POSNER, GARY, H, KALINDA, ALVIN, SOLOMAN, OH, SEONGHO, SINISHTAJ, SANDRA
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF TRAPPING
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Beschreibung
Zusammenfassung:	The invention provides novel trioxane dimers having formulae III, IV or V: methods for their preparation, pharmaceutical compositions containing these compounds, and methods for treating cancer and/or malaria using these compounds and compositions. L'invention concerne de nouveaux dimères de trioxane représentés par les formules (III), (IV) ou (V), des procédés de fabrication de ces composés, des compositions pharmaceutiques contenant ces composés, et des procédés de traitement du cancer et/ou du paludisme au moyen de ces composés et compositions.