BENZODIAZEPINE DERIVATIVES , THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF

The invention relates to benzodiazepine derivatives having PDE2 inhibitory activities, as well as therapeutic methods by administering said compounds, in particular for treating various diseases of the central or peripheral nervous system. It further deals with pharmaceutical compositions comprising...

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Bibliographische Detailangaben
Hauptverfasser: WAGNER, PATRICK, MONDADORI, CESARE, DURANTON, JEROME, ABARGHAZ, MUSTAPHA, BIONDI, STEFANO
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The invention relates to benzodiazepine derivatives having PDE2 inhibitory activities, as well as therapeutic methods by administering said compounds, in particular for treating various diseases of the central or peripheral nervous system. It further deals with pharmaceutical compositions comprising said compounds and methods for preparing said compounds. L'invention porte sur des dérivés de la benzodiazépine à activités inhibitrices du PDE2, et sur des méthodes thérapeutiques basées sur leur administration, en particulier pour le traitement de différentes maladies du système nerveux périphérique ou central. L'invention porte également sur des préparations pharmaceutiques comportant lesdits composés, et sur les méthodes de préparation desdits composés.