11-BETA-HYDROXYSTEROID DEHYDROGENASE-1-INHIBITOR-DIABETES-TYPE 2-1

Provided herein are compounds of the formula (I); as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for ex...

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Hauptverfasser: BILOTTA, JOSEPH ANTHONY, TILLEY, JEFFERSON WRIGHT, PIETRANICO-COLE, SHERRIE LYNN, FOTOUHI, NADER, MYERS, MICHAEL PAUL, GILLESPIE, PAUL, GOODNOW JR., ROBERT ALAN, HAYNES, NANCY-ELLEN, KOWALCZYK, AGNIESZKA, BANNER, BRUCE LESTER, SCOTT, NATHAN ROBERT, THAKKAR, KSHITIJ CHHABILBHAI, MAYWEG, ALEXANDER V, HAMILTON, MATTHEW MICHAEL
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Provided herein are compounds of the formula (I); as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome. La présente invention se rapporte à des composés de formule I) ; ainsi qu'à leurs sels pharmaceutiquement acceptables, dans lesquels les substituants sont tels que ceux présentés dans la description. Ces composés, et les compositions pharmaceutiques qui les contiennent, sont utiles pour le traitement de maladies telles que, par exemple, le diabète sucré de type II et le syndrome métabolique.