ASYMMETRIC REDUCTION OF 1,1,1-TRIFLUOROACETONE

The invention relates to a scalable biocatalytic process for the preparation of S- 1,1,1- trifluoro-2-propanol with a enantiomeric excess of > 99 % by asymmetric microbial reduction of 1,1,1-trifluoroacetone with Baker's yeast. L'invention concerne un procédé biocatalytique modulable de...

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Hauptverfasser:	KUPFER, ERNST, DOSWALD, STEPHAN, HANLON, STEVEN PAUL
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to a scalable biocatalytic process for the preparation of S- 1,1,1- trifluoro-2-propanol with a enantiomeric excess of > 99 % by asymmetric microbial reduction of 1,1,1-trifluoroacetone with Baker's yeast. L'invention concerne un procédé biocatalytique modulable de préparation of S-1,1,1-trifluoro-2-propanol à excès énantiomérique > 99 %, par réduction microbienne asymétrique de 1,1,1-trifluoroacétone au moyen de levure de boulangerie.