DIARYLSULFONE SULFONAMIDES AND USE THEROF

Compounds of Formula (I), or pharmaceutically acceptable salts thereof, are provided, which are modulators of secreted frizzled related protein-1. The compounds, and compositions containing the compounds, can be used to treat a variety of disorders, including osteoporosis. L'invention porte sur...

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Hauptverfasser:	MOLINARI, ALBERT, JOHN, KRISHNAMURTHY, GIRIJA, WOODWORTH, RICHARD, P, WEBB, MICHAEL, BYRON, WELMAKER, GREGORY, SCOTT, SHI, MENGXIAO, MOORE, WILLIAM, JAY, KERN, JEFFERY, CURTIS, WILSON, MATTHEW, ALLAN, GOPALSAMY, ARIAMALA, COMMONS, THOMAS, JOSEPH
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Compounds of Formula (I), or pharmaceutically acceptable salts thereof, are provided, which are modulators of secreted frizzled related protein-1. The compounds, and compositions containing the compounds, can be used to treat a variety of disorders, including osteoporosis. L'invention porte sur des composés de formule (I), ou sur leurs sels acceptables d'un point de vue pharmaceutique, qui sont des modulateurs de la protéine Frizzled sécrétée 1. Les composés et les compositions contenant ces composés peuvent être utilisés pour traiter diverses pathologiques telles que l'ostéoporose.