IMPROVED METHODS AND DEVICES FOR CONCENTRATION AND FRACTIONATION OF ANALYTES FOR CHEMICAL ANALYSIS INCLUDING MATRIX-ASSISTED LASER DESORPTION/IONIZATION (MALDI) MASS SPECTROMETRY (MS)

A device for pre-concentration and purification of analytes from biological samples, such as human serum, to be analyzed by Matrix-Assisted Laser Desorption Ionization Mass Spectrometry (MALDI MS) and methods of use thereof are provided. La présente invention se rapporte à un dispositif de concentra...

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Hauptverfasser: LOVEDAY, DONALD, BAKER, SHEILA, N, KUBAN, DANIEL, NORRIS, JEREMY, L, WITKOWSKI, CHARLES, E., II, CAPRIOLI, RICHARD, M, HARKINS, JAMES, B., IV, HAFEMAN, DEAN, G
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creator LOVEDAY, DONALD
BAKER, SHEILA, N
KUBAN, DANIEL
NORRIS, JEREMY, L
WITKOWSKI, CHARLES, E., II
CAPRIOLI, RICHARD, M
HARKINS, JAMES, B., IV
HAFEMAN, DEAN, G
description A device for pre-concentration and purification of analytes from biological samples, such as human serum, to be analyzed by Matrix-Assisted Laser Desorption Ionization Mass Spectrometry (MALDI MS) and methods of use thereof are provided. La présente invention se rapporte à un dispositif de concentration préalable et de purification de substances à analyser issues d'échantillons biologiques, tels que du sérum humain, destinés à être analysés par spectrométrie de masse à désorption-ionisation par impact laser assistée par matrice (MALDI-MS), ainsi qu'à des procédés d'utilisation associés.
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subjects CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PHYSICS
SEPARATION
TESTING
TRANSPORTING
title IMPROVED METHODS AND DEVICES FOR CONCENTRATION AND FRACTIONATION OF ANALYTES FOR CHEMICAL ANALYSIS INCLUDING MATRIX-ASSISTED LASER DESORPTION/IONIZATION (MALDI) MASS SPECTROMETRY (MS)
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