IMPROVED METHODS AND DEVICES FOR CONCENTRATION AND FRACTIONATION OF ANALYTES FOR CHEMICAL ANALYSIS INCLUDING MATRIX-ASSISTED LASER DESORPTION/IONIZATION (MALDI) MASS SPECTROMETRY (MS)

IMPROVED METHODS AND DEVICES FOR CONCENTRATION AND FRACTIONATION OF ANALYTES FOR CHEMICAL ANALYSIS INCLUDING MATRIX-ASSISTED LASER DESORPTION/IONIZATION (MALDI) MASS SPECTROMETRY (MS)

A device for pre-concentration and purification of analytes from biological samples, such as human serum, to be analyzed by Matrix-Assisted Laser Desorption Ionization Mass Spectrometry (MALDI MS) and methods of use thereof are provided. La présente invention se rapporte à un dispositif de concentra...

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Bibliographische Detailangaben
Hauptverfasser: LOVEDAY, DONALD, BAKER, SHEILA, N, KUBAN, DANIEL, NORRIS, JEREMY, L, WITKOWSKI, CHARLES, E., II, CAPRIOLI, RICHARD, M, HARKINS, JAMES, B., IV, HAFEMAN, DEAN, G
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PHYSICS
SEPARATION
TESTING
TRANSPORTING
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Beschreibung
Zusammenfassung:A device for pre-concentration and purification of analytes from biological samples, such as human serum, to be analyzed by Matrix-Assisted Laser Desorption Ionization Mass Spectrometry (MALDI MS) and methods of use thereof are provided. La présente invention se rapporte à un dispositif de concentration préalable et de purification de substances à analyser issues d'échantillons biologiques, tels que du sérum humain, destinés à être analysés par spectrométrie de masse à désorption-ionisation par impact laser assistée par matrice (MALDI-MS), ainsi qu'à des procédés d'utilisation associés.