BETA-POLYPEPTIDES THAT INHIBIT CYTOMEGALOVIRUS INFECTION

Disclosed are beta-polypeptides that mimic the coiled-coil regions of gB and gH by display of the key hydrophobic residues for coiled-coil packing along one face of beta-polypeptide 12-helix. The most potent inhibitor blocks infection of CMV with an IC50 of approximately 20 m. L'invention conce...

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Hauptverfasser:	COMPTON, TERESA, ENGLISH, EMILY, P, GELLMAN, SAMUEL, H, CHUMANOV, ROBERT, S
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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