ALTERED ACYLTRANSFERASE POLYPEPTIDES AND RELATED POLYNUCLEOTIDES

The present invention relates to novel acyltransferase polypeptides, as well as the polynucleotides that encode them, that are particularly useful in the production of beta-lactam intermediates and antibiotic compounds having adipoyl side chains. The present invention is also directed to related vec...

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Bibliographische Detailangaben
Hauptverfasser:	COX, ANTHONY, KREBBER, ANKE, TOBIN, MATTHEW, BOVENBERG, ROELOF, ARY, LANS, CHEN, YONG HONG, JENNE, STEPHANE J, TO LA CHING, CHARLENE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMES ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to novel acyltransferase polypeptides, as well as the polynucleotides that encode them, that are particularly useful in the production of beta-lactam intermediates and antibiotic compounds having adipoyl side chains. The present invention is also directed to related vectors, host cells, and methods for making and using the novel acyltransferase polypeptides. La présente invention concerne de nouveaux polypeptides d'acyltransférase, ainsi que les polynucléotides les codant, qui sont particulièrement utilisés dans la production d'intermédiaires de ß-lactam et de composés antibiotiques possédant des chaînes latérales d'adipoyle. Cette invention a aussi pour objet des vecteurs, des cellules hôtes et des méthodes de conception et d'utilisation desdits nouveaux polypeptides d'acyltransférase.