MODULATION OF CELLULAR HYPOXIA RESPONSES THROUGH NOTCH SIGNALLING

This invention relates to cellular responses to hypoxia, and, in particular, to the mediation of these responses by the Notch signalling pathway. Methods and means of influencing cellular responses to hypoxia by modulating the activity of the Notch signalling pathway are provided. Cette invention co...

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Bibliographische Detailangaben
Hauptverfasser:	GUSTAFSSON, MARIA, LENDAHL, URBAN, WHITELAW, MURRAY, RUAS, JORGE, WALLIS, TRISTAN, PAUL, GORMAN, JEFFREY, JOHN, LINKE, SARAH, POELLINGER, LORENZ, PEET, DANIEL, BONDESSON BOLIN, MARIA, PEREIRA, TERESA
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
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Beschreibung
Zusammenfassung:	This invention relates to cellular responses to hypoxia, and, in particular, to the mediation of these responses by the Notch signalling pathway. Methods and means of influencing cellular responses to hypoxia by modulating the activity of the Notch signalling pathway are provided. Cette invention concerne des réponses cellulaires à l'hypoxie et en particulier à la médiation de ces réponses par la voie de signalisation Notch. L'invention concerne également des moyens propres à influencer les réponses cellulaires à l'hypoxie par modulation de l'activité de la voie de modulation Notch.