PROCESS FOR THE PREPARATION OF IRINOTECAN HYDROCHLORIDE
The present invention is directed to a novel method for the preparation of high purity irinotecan hydrochloride. This can be achieved by eliminating the excess of the other reagent, bipi?eridinyl-1' -carbonyl chloride after it has reacted with 7-ethyl-10-hydroxy camptothecin and crystallizing t...
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