BINDING PROTEINS SPECIFIC FOR HUMAN MATRIPTASE
Binding proteins, such as fully human monoclonal antibodies and fragments thereof, directed to the antigen Matriptase and uses of such binding proteins are disclosed. Nucleotide sequences encoding, and amino acid sequences comprising heavy and light chain immunoglobulin molecules capable of binding...
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| creator | KEYT, BRUCE, A KING, CHADWICK LING, PETER, KOON BONG MADISON, EDWIN KANG, JASPAL, SINGH FOLTZ, IAN MORKOWSKI, STANISLAW, K MANCHULENKO, KATHY CHEN, FRANCINE SCATENA, CAROLINE, DARNE GODFREY, WAYNE, R RICHARDSON, JENNIFER, H |
| description | Binding proteins, such as fully human monoclonal antibodies and fragments thereof, directed to the antigen Matriptase and uses of such binding proteins are disclosed. Nucleotide sequences encoding, and amino acid sequences comprising heavy and light chain immunoglobulin molecules capable of binding to Matriptase are also disclosed. The invention also discloses cell lines expressing such immunoglobulin molecules and monoclonal antibodies to Matriptase. The antibodies can be used to treat diseases such as cancer.
L'invention concerne des protéines de liaison telles que des anticorps monoclonaux entièrement humains et des fragments de ceux-ci dirigés contre l'antigène matriptase, et des utilisations de ces protéines de liaison. L'invention concerne aussi les séquences nucléotidiques codant pour les molécules d'immunoglobuline à chaînes lourdes et légères pouvant se lier à la matriptase, et les séquences d'acides aminés comprenant lesdites molécules. L'invention concerne en outre des lignées cellulaires exprimant ces molécules d'immunoglobuline et des anticorps monoclonaux dirigés contre la matriptase. Ces anticorps sont utiles dans le traitement de maladies telles que le cancer. |
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L'invention concerne des protéines de liaison telles que des anticorps monoclonaux entièrement humains et des fragments de ceux-ci dirigés contre l'antigène matriptase, et des utilisations de ces protéines de liaison. L'invention concerne aussi les séquences nucléotidiques codant pour les molécules d'immunoglobuline à chaînes lourdes et légères pouvant se lier à la matriptase, et les séquences d'acides aminés comprenant lesdites molécules. L'invention concerne en outre des lignées cellulaires exprimant ces molécules d'immunoglobuline et des anticorps monoclonaux dirigés contre la matriptase. Ces anticorps sont utiles dans le traitement de maladies telles que le cancer.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>2006</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20060629&DB=EPODOC&CC=WO&NR=2006068975A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20060629&DB=EPODOC&CC=WO&NR=2006068975A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KEYT, BRUCE, A</creatorcontrib><creatorcontrib>KING, CHADWICK</creatorcontrib><creatorcontrib>LING, PETER, KOON BONG</creatorcontrib><creatorcontrib>MADISON, EDWIN</creatorcontrib><creatorcontrib>KANG, JASPAL, SINGH</creatorcontrib><creatorcontrib>FOLTZ, IAN</creatorcontrib><creatorcontrib>MORKOWSKI, STANISLAW, K</creatorcontrib><creatorcontrib>MANCHULENKO, KATHY</creatorcontrib><creatorcontrib>CHEN, FRANCINE</creatorcontrib><creatorcontrib>SCATENA, CAROLINE, DARNE</creatorcontrib><creatorcontrib>GODFREY, WAYNE, R</creatorcontrib><creatorcontrib>RICHARDSON, JENNIFER, H</creatorcontrib><title>BINDING PROTEINS SPECIFIC FOR HUMAN MATRIPTASE</title><description>Binding proteins, such as fully human monoclonal antibodies and fragments thereof, directed to the antigen Matriptase and uses of such binding proteins are disclosed. Nucleotide sequences encoding, and amino acid sequences comprising heavy and light chain immunoglobulin molecules capable of binding to Matriptase are also disclosed. The invention also discloses cell lines expressing such immunoglobulin molecules and monoclonal antibodies to Matriptase. The antibodies can be used to treat diseases such as cancer.
L'invention concerne des protéines de liaison telles que des anticorps monoclonaux entièrement humains et des fragments de ceux-ci dirigés contre l'antigène matriptase, et des utilisations de ces protéines de liaison. L'invention concerne aussi les séquences nucléotidiques codant pour les molécules d'immunoglobuline à chaînes lourdes et légères pouvant se lier à la matriptase, et les séquences d'acides aminés comprenant lesdites molécules. L'invention concerne en outre des lignées cellulaires exprimant ces molécules d'immunoglobuline et des anticorps monoclonaux dirigés contre la matriptase. Ces anticorps sont utiles dans le traitement de maladies telles que le cancer.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PHYSICS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>TESTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2006</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNBz8vRz8fRzVwgI8g9x9fQLVggOcHX2dPN0VnDzD1LwCPV19FPwdQwJ8gwIcQx25WFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8eH-RgYGZgZmFpbmpo5GxsSpAgCAWSbM</recordid><startdate>20060629</startdate><enddate>20060629</enddate><creator>KEYT, BRUCE, A</creator><creator>KING, CHADWICK</creator><creator>LING, PETER, KOON BONG</creator><creator>MADISON, EDWIN</creator><creator>KANG, JASPAL, SINGH</creator><creator>FOLTZ, IAN</creator><creator>MORKOWSKI, STANISLAW, K</creator><creator>MANCHULENKO, KATHY</creator><creator>CHEN, FRANCINE</creator><creator>SCATENA, CAROLINE, DARNE</creator><creator>GODFREY, WAYNE, R</creator><creator>RICHARDSON, JENNIFER, H</creator><scope>EVB</scope></search><sort><creationdate>20060629</creationdate><title>BINDING PROTEINS SPECIFIC FOR HUMAN MATRIPTASE</title><author>KEYT, BRUCE, A ; KING, CHADWICK ; LING, PETER, KOON BONG ; MADISON, EDWIN ; KANG, JASPAL, SINGH ; FOLTZ, IAN ; MORKOWSKI, STANISLAW, K ; MANCHULENKO, KATHY ; CHEN, FRANCINE ; SCATENA, CAROLINE, DARNE ; GODFREY, WAYNE, R ; RICHARDSON, JENNIFER, H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2006068975A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2006</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PHYSICS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>TESTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>KEYT, BRUCE, A</creatorcontrib><creatorcontrib>KING, CHADWICK</creatorcontrib><creatorcontrib>LING, PETER, KOON BONG</creatorcontrib><creatorcontrib>MADISON, EDWIN</creatorcontrib><creatorcontrib>KANG, JASPAL, SINGH</creatorcontrib><creatorcontrib>FOLTZ, IAN</creatorcontrib><creatorcontrib>MORKOWSKI, STANISLAW, K</creatorcontrib><creatorcontrib>MANCHULENKO, KATHY</creatorcontrib><creatorcontrib>CHEN, FRANCINE</creatorcontrib><creatorcontrib>SCATENA, CAROLINE, DARNE</creatorcontrib><creatorcontrib>GODFREY, WAYNE, R</creatorcontrib><creatorcontrib>RICHARDSON, JENNIFER, H</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KEYT, BRUCE, A</au><au>KING, CHADWICK</au><au>LING, PETER, KOON BONG</au><au>MADISON, EDWIN</au><au>KANG, JASPAL, SINGH</au><au>FOLTZ, IAN</au><au>MORKOWSKI, STANISLAW, K</au><au>MANCHULENKO, KATHY</au><au>CHEN, FRANCINE</au><au>SCATENA, CAROLINE, DARNE</au><au>GODFREY, WAYNE, R</au><au>RICHARDSON, JENNIFER, H</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>BINDING PROTEINS SPECIFIC FOR HUMAN MATRIPTASE</title><date>2006-06-29</date><risdate>2006</risdate><abstract>Binding proteins, such as fully human monoclonal antibodies and fragments thereof, directed to the antigen Matriptase and uses of such binding proteins are disclosed. Nucleotide sequences encoding, and amino acid sequences comprising heavy and light chain immunoglobulin molecules capable of binding to Matriptase are also disclosed. The invention also discloses cell lines expressing such immunoglobulin molecules and monoclonal antibodies to Matriptase. The antibodies can be used to treat diseases such as cancer.
L'invention concerne des protéines de liaison telles que des anticorps monoclonaux entièrement humains et des fragments de ceux-ci dirigés contre l'antigène matriptase, et des utilisations de ces protéines de liaison. L'invention concerne aussi les séquences nucléotidiques codant pour les molécules d'immunoglobuline à chaînes lourdes et légères pouvant se lier à la matriptase, et les séquences d'acides aminés comprenant lesdites molécules. L'invention concerne en outre des lignées cellulaires exprimant ces molécules d'immunoglobuline et des anticorps monoclonaux dirigés contre la matriptase. Ces anticorps sont utiles dans le traitement de maladies telles que le cancer.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE |
| title | BINDING PROTEINS SPECIFIC FOR HUMAN MATRIPTASE |
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