DIACYLGLYCEROL ACYLTRANSFERASE ASSAY

The present invention generally provides a method of measuring the biological activity of diacylglycerol acyltransferase (DGAT). Specifically, the present invention provides a method for rapid, mass screening of compounds which are able to modulate the biological activity of DGAT. More specifically,...

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Bibliographische Detailangaben
Hauptverfasser:	DE WAEPENAERT, KATHARINA, ANTONIA, GERMANIA, JOSEPHA, MAURITA, VAN HECKE, GEERT, MARIA, ROBERT, BERWAER, MONIQUE, JENNY, MARIE, PEETERS, DANIELLE, CELINE, GEORGETTE, VERMEULEN, PETER, GUIDO, IDA
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention generally provides a method of measuring the biological activity of diacylglycerol acyltransferase (DGAT). Specifically, the present invention provides a method for rapid, mass screening of compounds which are able to modulate the biological activity of DGAT. More specifically, the present invention provides an assay system for measuring DGAT activity based on the use of particular micelles with the FlashPlate technology. La présente invention porte, de manière générale, sur une méthode permettant de mesurer l'activité biologique de diacylglycérol acyltransférase (DGAT). De manière spécifique, invention porte sur une méthode de recherche systématique et rapide de composés capables de moduler l'activité biologique de DGAT. Plus spécifiquement, invention porte sur un système de deux flashes permettant de mesurer l'activité de DGAT en utilisant des micelles particulières selon la technologie FlashPlate .