SUBSTITUTED 5-OXO PYRAZOLES AND [1,2,4]TRIAZOLES AS ANTIVIRAL AGENTS

The present invention provides compounds of formula (I) wherein X and R1-R7 are as defined herein. Compositions containing these compounds, and methods for inhibiting HCV RNA-dependent RNA polymerase and treating hepatitis C and related disorders using these compounds and compositions are also provi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	WANG, TONG, SHIPPS, GERALD, W., JR, ROSNER, KRISTEN, E, COOPER, ALAN, B, GIRIJAVALLABHAN, VIYYOOR, MOOPIL, CURRAN, PATRICK, J
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention provides compounds of formula (I) wherein X and R1-R7 are as defined herein. Compositions containing these compounds, and methods for inhibiting HCV RNA-dependent RNA polymerase and treating hepatitis C and related disorders using these compounds and compositions are also provided. La présente invention porte sur des composés de formule (I) dans laquelle X et R1-R7 sont tels que définis dans la demande. L'invention porte également sur des compositions contenant ces composés et sur des méthodes d'inhibition de l'ARN polymérase dépendant de l'ARN du virus de l'hépatite C (VHC), ainsi que sur des méthodes de traitement de l'hépatite C et des troubles apparentés utilisant ces composés et ces compositions.