METHOD OF SEPARATING AND PURIFYING YTTRIUM-90 FROM STRONTIUM-90

The present invention provides a method of separating and purifying Yttrium 90 (Y-90) from Strontium 90 (Sr-90). In addition, a zirconium (Zr) clean-up step for the Y-90 is provided. Uses of the Y-90 purified by the method include cancer research and treatment. Y-90 is particularly useful in cell di...

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Bibliographische Detailangaben
1. Verfasser:	BRAY, LANE, ALLAN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM,CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THERARE-EARTH METALS CONVERSION OF CHEMICAL ELEMENTS DECONTAMINATION ARRANGEMENTS THEREFOR INORGANIC CHEMISTRY METALLURGY NUCLEAR ENGINEERING NUCLEAR PHYSICS PHYSICS PROTECTION AGAINST X-RADIATION, GAMMA RADIATION, CORPUSCULARRADIATION OR PARTICLE BOMBARDMENT RADIOACTIVE SOURCES TREATING RADIOACTIVELY CONTAMINATED MATERIAL
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Beschreibung
Zusammenfassung:	The present invention provides a method of separating and purifying Yttrium 90 (Y-90) from Strontium 90 (Sr-90). In addition, a zirconium (Zr) clean-up step for the Y-90 is provided. Uses of the Y-90 purified by the method include cancer research and treatment. Y-90 is particularly useful in cell directed therapy, e.g., where the Y 90 is attached directly or indirectly to a targeting molecule such as an antibody. La présente invention concerne un procédé pour séparer et purifier l'yttrium 90 (Y-90) mélangé avec du strontium 90 (Sr-90). Un stade de purification de zirconium (Zr) est aussi prévu. L'utilisation d'Y-90 purifié par le procédé de l'invention concerne la recherche et le traitement en matière de cancer. Y-90 est particulièrement utile dans la thérapie cellulaire, par exemple, lorsque Y-90 est attaché directement ou indirectement à une molécule de ciblage telle qu'un anticorps.