THIAZOLO-NAPHTHYL ACIDS AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR-1

THIAZOLO-NAPHTHYL ACIDS AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR-1

The present invention relates to thiazolo-naphthyl acids of the formula (I) and methods of using them to modulate PAI-1 expression and to treat PAI-1 related disorders. L'invention porte sur des acides thiazolo-naphthyliques de formule (I) et sur leurs méthodes d'utilisation pour moduler l...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: COMMONS, THOMAS, JOSEPH
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention relates to thiazolo-naphthyl acids of the formula (I) and methods of using them to modulate PAI-1 expression and to treat PAI-1 related disorders. L'invention porte sur des acides thiazolo-naphthyliques de formule (I) et sur leurs méthodes d'utilisation pour moduler l'expression du PAI-1 et traiter les troubles liés au PAI-1.