RESOLUTION OF RACEMIC ORGANIC ACIDS WITH (1S, 4S)-4[3,4-DICHLOROPHENYL]-1,2,3,4- TETRAHYDRO-N-METHYL-1-NAPHTHALONEAMINE

RESOLUTION OF RACEMIC ORGANIC ACIDS WITH (1S, 4S)-4[3,4-DICHLOROPHENYL]-1,2,3,4- TETRAHYDRO-N-METHYL-1-NAPHTHALONEAMINE

The present invention relates to novel chiral resolving agents and a process for resolution of racemic organic acids and their derivatives of the formula (+, -)-R1R2CHCOOR3 with Cis- (1S,4S)-4 [3,4-dichlorophenyl]-1,2,3,4-tetrahydro-N-methyl-1-naphthaloneamine and its Cis-(lR,4R)-isomer as well as T...

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Bibliographische Detailangaben
Hauptverfasser: CHAVA, SATYANARYANA, BANDARI, MOHAN, MADHURESH, KUMAR, SETHI
Format: Patent
Sprache:eng ; fre
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention relates to novel chiral resolving agents and a process for resolution of racemic organic acids and their derivatives of the formula (+, -)-R1R2CHCOOR3 with Cis- (1S,4S)-4 [3,4-dichlorophenyl]-1,2,3,4-tetrahydro-N-methyl-1-naphthaloneamine and its Cis-(lR,4R)-isomer as well as Trans-(1S,4R)-4[3,4-dichlorophenyl]-1,2,3,4-tetrahydro-N-methyl-1-naphthaloneamine and its Trans-(1R,4S)-isomer. La présente invention a trait à de nouveaux agents de résolution chirale et à un procédé pour la résolution d'acides organiques racémiques et leurs dérivés de formule (+, -)-R1R2CHCOOR3 avec Cis- (1S,4S)-4 [3,4-dichlorophényl]-1,2,3,4-tétrahydro-N-méthyl-1-naphtaloneamine et son isomère Cis-(lR,4R) ainsi que son isomère Trans-(1S,4R)-4[3,4-dichlorophényl]-1,2,3,4-tétrahydro-N-méthyl-1-naphtaloneamine et son Trans-(1R,4S).