PREPARATION OF PHARMACEUTICAL COMPOSITIONS CONTAINING NANOPARTICLES

PREPARATION OF PHARMACEUTICAL COMPOSITIONS CONTAINING NANOPARTICLES

Materials and methods for preparing pharmaceutical nanoparticle suspensions or dispersions, granulations and dosage forms are disclosed. The methods employ a modular high-pressure spray homogenizer coupled to a wet granulator to form stabilized nanoparticle suspensions and granulations. L'inven...

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Bibliographische Detailangaben
Hauptverfasser: LODAYA, MAYUR, P, GALLI, CHRISTOPHER, C, VEMAVARAPU, CHANDRA, MOLLAN, MATTHEW, J., JR, POLAK, WILLIAM, MICHAEL, SHAH, UMANG
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:Materials and methods for preparing pharmaceutical nanoparticle suspensions or dispersions, granulations and dosage forms are disclosed. The methods employ a modular high-pressure spray homogenizer coupled to a wet granulator to form stabilized nanoparticle suspensions and granulations. L'invention porte sur des matériaux et procédés de préparation de suspensions, de dispersions, de granulations et de formes posologiques, de nanoparticules, à usage pharmaceutique. Lesdits procédés recourent à un homogénéisateur modulaire de pulvérisation à haute pression couplé à un granulateur humide pour former des suspensions et granulations stabilisées de nanoparticules.