METHODS FOR IDENTIFYING AGENTS USEFUL FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES

The present invention is directed to methods for identifying agents that are useful for the treatment of neurodegenerative diseases. Examples of such diseases include Alzheimer's disease, Parkinson's disease and Huntington's disease. The methods involve testing such agents against gen...

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Bibliographische Detailangaben
Hauptverfasser:	RHOADES, KRISTINA, L, WONG-STAAL, FLOSSIE, MA, HONGWEN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
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Beschreibung
Zusammenfassung:	The present invention is directed to methods for identifying agents that are useful for the treatment of neurodegenerative diseases. Examples of such diseases include Alzheimer's disease, Parkinson's disease and Huntington's disease. The methods involve testing such agents against genes or proteins disclosed herein and ascertaining the degree of protection provided by such agents against induction of neuronal cell death. The use of such agents for treating neurodegenerative diseases is also described. Cette invention concerne des procédés permettant d'identifier des agents servant au traitement de maladies neurodégénératives telles que la maladie d'Alzheimer, la maladie de Parkinson et la maladie de Huntington. Les procédés de cette invention consistent à tester ces agents contre des gènes ou des protéines décrits dans cette invention et à déterminer le degré de protection conféré par ces agents contre l'induction de la mort des cellules neuronales. Cette invention concerne également l'utilisation de ces agents pour traiter les maladies neurodégénératives.