DERIVATIVES OF ION CHANNEL MODULATING COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF

This invention is directed to PEGlyated derivatives, drug conjugates and isotopic derivatives of certain ion channel modulating compounds. Pharmaceutical compositions and methods of use of also disclosed L'invention concerne des dérivés PEGlyatés, des conjugués médicamenteux et des dérivés isot...

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Hauptverfasser:	CHOI, LEWIS, SIU, LEUNG, JUNG, GRACE, MOORE, ALAN, F, DAVIDOFF, ALLEN, W, EZRIN, ALAN, M, CHOU, DOUG, TA, HUANG, CLOHS, LILIAN, BEATCH, GREGORY, N, PLOUVIER, BERTRAND, M.C, GRANT, SHEILA, M, CHEU, ELIZABETH, L.S, BARRETT, ANTHONY, G.M
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY DERIVATIVES THEREOF HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SUGARS
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Beschreibung
Zusammenfassung:	This invention is directed to PEGlyated derivatives, drug conjugates and isotopic derivatives of certain ion channel modulating compounds. Pharmaceutical compositions and methods of use of also disclosed L'invention concerne des dérivés PEGlyatés, des conjugués médicamenteux et des dérivés isotopiques de certains composés de modulation des canaux ioniques. L'invention concerne également des compositions pharmaceutiques et des méthodes d'utilisation.