PROCESSES FOR THE PREPARATION OF ROCURONIUM BROMIDE AND INTERMEDIATES THEREOF

PROCESSES FOR THE PREPARATION OF ROCURONIUM BROMIDE AND INTERMEDIATES THEREOF

A novel process for preparing (2beta,3alpha,5alpha,16alpha,17beta)-17-acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl) androstane, a known intermediate in the synthesis of the skeletal muscle relaxant rocuronium bromide, is disclosed. L'invention concerne un nouveau procédé permettant de...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: ADAR, ELIEZER, FIZITZKI, TAMIR, FREGER, BORIS, FRIEDMAN, ODED, KASPI, JOSEPH, MANASCU, IOSEF, SONDACK, DAVID, ARAD, ODED, WEISMAN, ALEXANDER
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
STEROIDS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A novel process for preparing (2beta,3alpha,5alpha,16alpha,17beta)-17-acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl) androstane, a known intermediate in the synthesis of the skeletal muscle relaxant rocuronium bromide, is disclosed. L'invention concerne un nouveau procédé permettant de préparer un (2beta,3alpha,5alpha,16alpha,17beta)-17-acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl) androstane, un intermédiaire connu dans la synthèse du bromure de rocuronium utilisé comme relaxant des muscles du squelette.