COMPOSITIONS AND METHODS OF USE FOR A FIBROBLAST GROWTH FACTOR

The present invention generally relates to compositions and methods of use for a fibroblast growth factor ("FGF"). More particularly, the present invention relates to a nucleotide polymorphism (SNP) of FGF-20, and its fragments, derivatives, variants, homologs, and analogs, as well as thei...

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Bibliographische Detailangaben
Hauptverfasser: LEPLEY, DENISE, M, MEZES, PETER, EICHEN, JOSEPH, MILLER, CHARLES, E, ALSOBROOK, JOHN, II
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention generally relates to compositions and methods of use for a fibroblast growth factor ("FGF"). More particularly, the present invention relates to a nucleotide polymorphism (SNP) of FGF-20, and its fragments, derivatives, variants, homologs, and analogs, as well as their uses in wound healing, and prevention and/or treatment of certain diseases, including but are not limited to, stroke, radiation sickness, mucositis, inflammatory bowel disease, and inflammation (osteoarthritis and rheumatoid arthritis). De façon générale, La présente invention concerne des compositions et des méthodes utiles pour facteur de croissance des fibroblastes ("FGF"). Plus particulièrement, l'invention concerne un polymorphisme de nucléotides (SNP) de FGF-20, et ses fragments, dérivés, variantes, homologues et analogues, ainsi que leurs utilisations pour la cicatrisation des blessures, la prévention et/ou le traitement de certaines maladies, dont, notamment, les attaques, la maladie des rayons, la mucosite, la maladie intestinale inflammatoire et les inflammations (ostéoarthrose et polyarthrite rhumatoïde).