PROTEIN BASED TNF-ALPHA VARIANTS FOR THE TREATMENT OF TNF-ALPHA RELATED DISORDERS

The invention relates to novel proteins with TNF-alpha antagonist activity and nucleic acids encoding these proteins. The invention further relates to the use of the novel proteins in the treatment of TNF-alpha related disorders. L'invention concerne de nouvelles protéines à activité antagonist...

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Bibliographische Detailangaben
Hauptverfasser: DESJARLAIS, JOHN, R, ZALEVSKY, JONATHAN, SZYMKOWSKI, DAVID, EDMUND, STEED, PAUL, MICHAEL
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The invention relates to novel proteins with TNF-alpha antagonist activity and nucleic acids encoding these proteins. The invention further relates to the use of the novel proteins in the treatment of TNF-alpha related disorders. L'invention concerne de nouvelles protéines à activité antagoniste du TNF-alpha et des acides nucléiques codant ces protéines. L'invention concerne en outre l'utilisation de ces protéines dans le traitement de troubles associés au TNF-alpha.