LENTIVIRAL APOE2 GENE THERAPY

The present invention is a method for inhibiting or reducing disease progression in subjects suffering from conditions or diseases related to the Aß peptide, including Alzheimer's disease, Down's syndrome, cerebral amyloid angiopathy, mild cognitive impairment, and the like. The method com...

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Bibliographische Detailangaben
Hauptverfasser:	VERMA, INDER, MOHAN, BALES, KELLY, RENEE, MARR, ROBERT, A, DODART, JEAN-COSME, FRANCOIS, PAUL, STEVEN, MARC
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention is a method for inhibiting or reducing disease progression in subjects suffering from conditions or diseases related to the Aß peptide, including Alzheimer's disease, Down's syndrome, cerebral amyloid angiopathy, mild cognitive impairment, and the like. The method comprises administering an apoE2 lentiviral vector to the subject. La présente invention concerne une technique permettant d'inhiber ou de réduire la progression d'une maladie chez des sujets souffrants de pathologies ou de maladies liées au peptide Ass, notamment la maladie d'Alzheimer, le syndrome de, l'angiopathie amyloïde cérébrale, la déficience cognitive moyenne et d'autres maladies similaires. Cette technique consiste administrer un vecteur lentiviral apoE2 au patient.