2-METHOXYMETHYL-3-(3,4-DICHLOROPHENYL)-8-AZABICYCLO[3.2.1]OCTANE TARTRATE SALTS

This invention relates to novel (1R,2R,3S,5S)-2-methoxymethyl-3-(3,4dichlorophenyl)-8-azabicyclo[3.2. 1 ]octane tartrate salts, such as L-tartrate monohydrates and anhydrates. The salts are useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use o...

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Hauptverfasser:	FROESTRUP, BRIAN, JENSEN, KLAUS, SNEJ, WAETJEN, FRANK
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention relates to novel (1R,2R,3S,5S)-2-methoxymethyl-3-(3,4dichlorophenyl)-8-azabicyclo[3.2. 1 ]octane tartrate salts, such as L-tartrate monohydrates and anhydrates. The salts are useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these salts in a method for therapy and to pharmaceutical compositions comprising the salts of the invention. L'invention concerne des sels de (1R,2R,3S,5S)-2-méthoxyméthyl-3-(3,4dichlorophényl)-8-azabicyclo[3.2. 1 ] octane tartrate, tels que des monohydrates et des anhydrates de L-tartrate. Les sels sont utiles comme inhibiteurs du recaptage des neurotransmetteurs monoamine. D'autres modes de réalisation de l'invention concernent l'utilisation de ces sels dans une méthode de thérapie et des compositions pharmaceutiques renfermant les sels selon l'invention.