ERK7 AND ERK8, NOVEL DIAGNOSTIC MARKERS FOR CANCER

The present invention is directed in part to the discovery of a novel signal transduction pathway that regulates estrogen responsiveness. Human extracellular signal-regulated kinase 8 (ERK8) has been discovered by applicants to preferentially enhance the destruction of ERalpha , and loss of ERK8 is...

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Bibliographische Detailangaben
Hauptverfasser: HENRICH, LORIN, M, SMITH, JEFFREY, A, LANNIGAN-MACARA, DEBORAH, A
Format: Patent
Sprache:eng ; fre
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